Have you ever noticed that why some people can eat without worrying about weight gain while others almost starve themselves to stay fit and in shape?
Well, it seems that the experts have discovered the plausible answer.
Scientists from the University of Cambridge in England have observed a gene mutation known as KSR2 that is accountable for hunger pangs in overweight patients. According to the researchers this gene is responsible for decreased metabolism.
Metabolism is actually the rate at which excess calories are utilized by your body.
Previous studies have highlighted the fact that KSR2 gene was responsible for obesity in rats. The gene hampered the energy balance and metabolism in rats but its role in human beings was not very clear.
In order to analyze the role of KSR2 gene in obesity, around 2,101 kids with childhood obesity were enrolled for the study.
The outcomes were contrasted with genetic sequence of kids who were with normal weight and healthy.
The scientists noticed that children with KSR2 genetic mutation were vulnerable to raised appetite, decreased metabolism slow heart rate even severe insulin resistance.
The lead researcher Sadaf Farooqi of the University of Cambridge mentioned, “This variation between people is largely influenced by genetic factors. The discovery of a new obesity gene, KSR2, demonstrates that genes can contribute to obesity by reducing metabolic rate – how well the body burns calories.”
The experts were of the opinion that in coming times this KSR2 gene can become a better option or treating obesity and type-2 obesity.
The further added, “These observations and our in vitro findings suggest that pharmacological approaches based on the modulation of KSR2 activity could represent a novel potential therapeutic strategy for the treatment of obesity and type 2 diabetes.”
The study was published in the Journal of Cell.